Difference Between Smallpox and Chickenpox

Difference Between Small Pox and Chicken Pox

Difference between chickenpox and  smallpox is tabulated below

Feature	Smallpox	Chickenpox
Caused by:	Smallpox is caused by the Variola virus	Chickenpox is caused by Varicella zoster virus
Incubation Period:	It is 7-17 days for smallpox	It is 7-21 days for chickenpox
Prodromal Symptoms	These are Severe in smallpox	These are Mild in chickenpox
Distribution Of Rash	Centrifugal for smallpox	Centripetal for chickenpox
Palms and Soles	Frequently Involved in smallpox	Seldom affected in chickenpox
Axilla	Usually free in smallpox	Axilla is affected in chickenpox
Rash	In smallpox it is Predominant on extensor surface, deep-seated, vesicles are multilocular, only one stage of rash is seen at one time and there is no inflammation around the rash.	In Chickenpox Predominant on flexor surface, Superficial, Vesicles are unilocular, dewdrop like different stages of rash can be seen at one time and there is an area of inflammation around the rash
Evolution Of Rash	Slow in smallpox	Rapid in chickenpox
Fever:	In smallpox, it Subsides   with the appearance of rash but the temperature may rise again in the pustular stage	In chickenpox, Temperature rises with each crop of rash

Chicken Pox Rash

Small Pox Rash.