MRCP Pearls
Cryoglobulinemia, Cryoglobulinemia Causes, Symptoms & Treatment
Cryoglobulinemia causes
- Hep C
- Myeloma,
- Waldenstrom’s macroglobulinemia,
- SLE,
- Rheumatoid arthritis,
- Sjogren’s syndrome,
Symptoms,
Immunoglobulins precipitate when cooled under skin, ulcers, rashes, gangrene, Raynaud’s phenomenon.
Treatment.
Plasma exchange,
Chemotherapy,
Treat the cause.
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