Cryoglobulinemia, Cryoglobulinemia Causes, Symptoms & Treatment

Cryoglobulinemia causes 

1. Hep C
2. Myeloma, 
3. Waldenstrom’s macroglobulinemia, 
4. SLE, 
5. Rheumatoid arthritis, 
6. Sjogren’s syndrome, 

Symptoms, 

Immunoglobulins precipitate when cooled under skin, ulcers, rashes, gangrene, Raynaud’s phenomenon. 

Treatment.

Plasma exchange, 

Chemotherapy, 

Treat the cause.