Gastric Lymphoma
Types
There are two different types of lymphoma
- Part of systemic lymphoma with gastric involvement (32%)
- Primary involvement of the GIT (MALT Tumors)
Occurrence:
10 – 20% of all lymphomas occur in the abdomen
50% of those are gastric in nature
Risk factors
Chronic H. Pylori infection (due to chronic stimulation of the MALT)
In early stages of disease Treatment of H. pylori infection leads to regression of the disease
Early stages also referred to as pseudo-lymphoma
Indolent for long periods
Low incidence of
- Spread to lymph nodes
- Involvement of bone marrow
- Therefore much better prognosis
Mostly involves the antrum
At time of presentation
- Larger than 10 cm (50%)
- More than 1 focus (25%)
- Ulcerated (30 – 50%)
Pattern of metastasis similar to gastric carcinoma
Signs and symptoms
Occur late and are vague (dyspepsia,epigastric pain,hematemesis,melena &wt loss)
Diagnosis
based on histology
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