Ezetimibe (Zetia) 

Mechanism Of Action.
Ezetimibe acts within intestine to reduce cholesterol absorption. Cholesterol is absorbed from the small intestine by a process that includes specific transporters that have not been completely characterized. Ezetimibe appears to block one or more of these cholesterol transporters, reducing cholesterol absorption.

Therapeutic Uses:
Ezetimibe used alone produces a reduction in plasma cholesterol of about 18 percent and about 10 percent decline in plasma triglicerides levels. When combined with a statin, reduction in plasma cholesterol as high as 72 percent have been reported. 

Adverse effects.
Although well tolerated. Adverse effects include;
1. fatigue 
2. abdominal pain
3. diarrhea