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Causes Of Infectious Esophagitis (Oesophagitis)
1. Bacteremia
2. Viremia
3. Herpes simplex
4. Cytomegalovirus
5. Candidiasis
6. Mucormycosis
7. Aspergillosis

Causes of Chemical Esophagitis:
1. Ingested irritants (e.g alcohol, acids, alkalies and hot fluids)
2. Heavy smoking
3. Anticancer drugs
4. Uremia
5. Radiotherapy

Morphology:
1. Non specific features:
a) Severe inflammation,
b) Superficial necrosis
c) Ulceration with formation of granulation tissue and fibrosis

2. Specific features:
a) Adherent gray white psedo-membranes (in case of candidiasis)
b) Punched out ulcers of the esophageal mucosa (in case of herpes infection)
c) Tablet or capsule sticking in esophagus (incase of chemical or drug esophagitis)
d) In case of radiation esophagitis there will be Mucosal atrophy, submucosal fibrosis and Vascular intimal thickening

Clinical Features and signs (infectious esophagitis)

1. dysphagia
2. painful swallowing
3. heart burn
4. Nausea
5. Chest pain
or infectious esophagitis may be asymptomatic.

Treatment of infectious esophagitis:
Treatment varies with the causative agent.
it is treated with antibacterial, antiviral or antifungal drugs depending on the causative agent that is whether it is a bacteria, virus or fungus.
 
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