Fate Of Thrombus: What Happens after Thrombus Formation ?

Fate Of Thrombus. 

           Once Thrombus is formed

1. It may propagate and increase in size and cause obstruction of some critical blood vessels (for example coronary artery)
2. It may detach from its attachment and may embolize.
3. It may be removed by fibrinolytic activity and blood flow is established again.
4. It may undergo organization into the fibrinnous thrombus
5. Organized Thrombus may become re-canalize (capillary channels are formed in the organized thrombus) thus re-establishing continuity of lumen of the vessel.
6. Center of thrombus may undergo enzymatic digestion and softens due to release of lysosomal enzymes from the trapped leukocytes and platelets, such soften debris is ideal culture medium for bacterial growth.

TOPICS Covered.

• Thrombosis
• mechanism of thrombus formation
• Types Of Thrombus
• Difference between venous thrombi and postmortem clots
• Fate of Thrombi
• Clinical manifestations and treatment