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Coomb's test is very helpful in making a diagnosis of hemolytic anemia. Once a patient is found to have anemia, with raised bilirubin and raised retic count, hemolysis becomes the most likely possibility. Coomb's test is of two types. 1. Direct Coomb's test 2. Indirect Coomb's test. Direct Coomb's test: In case of direct Coomb's test, patient's RBC's are washed clear of plasma and are mixed with Coomb's serum (antihuman globulins), if agglutination occurs, it means the Direct Coomb's test is positive. If the direct Coomb's test is positive it means the patient has autoimmune hemolytic anemia. Indirect Coomb's test.  In indirect Coomb's test, the patient's serum is taken instead of RBCs and this serum is then mixed and incubated with RBCs with a known antigen if the patient's serum contains antibodies against the RBCs antigens then antibody-antigens complexes are formed, then coombs serum is added to the sample, if ...

Pakistan Institute of medical sciences has a separate department of Thalassemia and BMT (Bone Marrow Transplant) which are headed by Dr Tazeen and Dr Itrat respectively. In Pakistan, it is estimated that every year around 5000 children are born with Thalassemia. Most of the population of these children belong to the lower class and those people who are uneducated. “We have counseled the parents number of times about avoiding next Thalassemia baby. We have told them the methods which can be chosen to avoid having them. We tell them that it is very important to do chorionic villous sampling, a test which is used to diagnose Thalassemia in-utero. But still they don’t understand and next time come with another affected baby. That is why the population of Thalassemia affected children is increasing with-in the population of these poor and un-educated people” said Dr. Tazeen, the head of Thalassemia center PIMS. The treatment of Thalassemia is very costly. Every month many of these children...