Drug of choice is that drug which is known to be most effective in order to cure an infection or disease. A drug of choice should be accessible, cost-effective, easily tolerable, safe, and most importantly effective against the disease-causing pathogen.

Following is the list of few of drugs that are used in the common infections.

Pathogen
Disease
Drug of Choice
Actinomyces
Actinomycosis
Penicillin G
Bacillus anthracis
Anthrax
Ciprofloxacin, Tetracyclines
Bordetella pertussis
Whooping cough
Erythromycin
Borrelia burgdorferi
Lyme disease
Tetracycline
Campylobacter
Acute inflammatory diarrhea
Ciprofloxacin
Candida
Vaginal candidiasis
Systemic candidiasis
Miconazole
Fluconazole
Chlamydia trachomatis
Pelvic inflammatory disease
Doxycycline
Chlamydia pneumonia
Pneumonia
Tetracycline
H. influenza
Pneumonia, Meningitis
3rd Gen Cephalosporin
H. pylori
Gastric ulcers
Metronidazole + Tetracycline
Klebsiella
Pneumonia
UTI
3rd Gen Cephalosporin,
Quinolones
Legionella
Legionnaire's disease
Erythromycin
M. Tuberculosis
Tuberculosis
Isoniazid + Rifampin + Pyrazinamide + Ethambutol
M. leprae
Leprosy
 Dapsone + Rifampin
M. pneumonia
Atypical pneumonia
Erythromycin
N. gonorrhea
Gonorrhea
Ceftriaxone
N. meningitis
Meningitis
Penicillin G
Nocardia
Pneumonia
Trimethoprim/Sulfamethoxazole
Proteus
UTI
Quinolones
Rickettsia
Spotted fever, Typhus
Tetracycline
Salmonella typhi
Typhoid fever
Ciprofloxacin / Trimethoprim+Sulfamethoxazole
Shigella
Dysentery
Trimethoprim+Sulfamethoxazole
Staph aureus
Skin infection, sepsis, osteomyelitis
Dicloxacillin, nafcillin or oxacillin
Strep. Pyogenes
Pharyngitis, erysipelas
Penicillin G or V
Strep viridans
Endocarditis
Penicillin + Aminoglycoside
Treponema pallidum
Syphilis
Penicillin G
Tropheryma whippelii
 Whipple’s disease
Trimethoprim/Sulfamethoxazole
Trichomonas
Trichomoniasis
Metronidazole
Vibrio cholera
Cholera
Tetracycline (+fluids)
Yersinia pestis
Plague (Black Death)
Streptomycin


 
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