Difference Between H Pylori and Autoimmune Gastritis

Difference Between H Pylori and Autoimmune Gastritis

	H.Pylori associated.	A.immune
Inflammatory infiltrate.	Neutrophills,Plasma cells	Lymphocytes, macrophages.
Acid production	Increased or slightly decreased	Decreased.
Gastrin	normal to decreased	Increased
Other lesions	Hyperplastic/infiltrative polyps	Neuro- endocrine hyperplasia
Serology	Antibodies sensitive  to H.pylori are found	Antibodies  to intrinsic  factor.
Sequelae	Peptic ulcer, Adenocarcinoma	Atrophy, pernicious  anaemia, Adeno- carcinoma, carcinoid tumor
Association	Poverty, overcrowding	AutoImmne  diseases; Thyroiditis, D.mellitis, Graves disease

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