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Difference Between H Pylori and Autoimmune Gastritis




Difference Between H Pylori and Autoimmune Gastritis

H.Pylori associated.
A.immune
Inflammatory infiltrate.
Neutrophills,Plasma cells
Lymphocytes,
macrophages.

Acid production
Increased or slightly decreased
Decreased.
Gastrin
normal to decreased
Increased
Other lesions
Hyperplastic/infiltrative polyps
Neuro-
endocrine
hyperplasia

Serology
Antibodies sensitive
 to H.pylori are found
Antibodies 
to intrinsic
 factor.

Sequelae
Peptic ulcer,Adenocarcinoma


Atrophy,
pernicious 
anaemia,
Adeno-
carcinoma,
carcinoid
tumor




Association




Poverty,overcrowding




AutoImmne 
diseases;
Thyroiditis,
D.mellitis,
Graves disease


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