Mebendazole 100 mg, Indications, Dose and Treatment Course, Brand Names Available In Pakistan

Mebendazole and albendazole are benzimidazole carbamates that bind with high affinity to parasite-free B-tubulin to inhibit its polymerization and microtubule assembly. These agents also irreversibly inhibit glucose uptake by nematodes; the resulting glycogen depletion and decreased ATP production immobilize the intestinal parasite, which is then cleared from the GI tract. 

Indications:

Mebendazole is the drug of choice for the treatment of Trichuris trichuria (whipworm), Enterobius vermicularis (horse pinworm, pinworm), Ascaris lumbricoides (roundworm), as well as hookworm Ancylostoma duodenale and Necator americanus. For all these helminth mebendazole has success rates of at least 90 to 95%. It is also recommended for the treatment of Echinococcus granulosus and E. multilocularis infections

Mebendazole is available in Pakistan in various brand names. Each brand name along with manufacturing pharmaceutical industry is given below.

ALMEB	ALSON PHARMACEUTICALS
BELMENTIC	PARAMOUNT PHARMACEUTICALS
BELMENTIC	PARAMOUNT PHARMACEUTICAL
BELMENTIC	PARAMOUNT PHARMACEUTICALS
BENDAMOX	UNEXO LABS (PVT) LTD
ERIZOLE	EFROZE CHEMICAL INDUSTRIES (PVT) LTD.
GEOZOLE	GEOFMAN PHARMACEUTICALS
GEOZOLE	GEOFMAN PHARMACEUTICALS
G-WORM	OLIVE LABORATORIES
HELMOX	LAHORE CHEMICAL & PHARMACEUTICAL WORKS (PVT) LTD
MEBEN	SPENCER PHARMA
MEBENDAZOLE	BENSON PHARMACEUTICALS.
MEBENDAZOLE	BENSON PHARMACEUTICALS.
MEBEROWN	CROWN PHARMACEUTICALS	’
MEBNAGEN	GENERA PHARMACEUTICALS
MEBNAGEN	GENERA PHARMACEUTICALS
MENAREX	REX PHARMACEUTICALS PAKISTAN
MENDAZOLE	VALOR PHARMACEUTICALS
MEZONIL	DR. RAZA PHARMA (PRIVATE) LIMITED
NEMAZOLE	GLAXOSMITHKLINE
PANAMOX	LIFE LINE PHARMACEUTICALS (PVT.) LTD.
PANAMOX	LIFE LINE PHARMACEUTICALS (PVT.) LTD.
PAREX	INNVOTEK PHARMACEUTICALS
PROVERM	PHARMEDIC (PVT) LTD.
SPHINX	LIBRA PHARMACEUTICALS (PVT) LTD
TAGAMEB	TAGMA PHARMA (PVT) LTD.
VERMIN	ADAMJEE PHARMACEUTICALS (PVT) LTD.
VERMOX	JANSSEN-CILAG
WARTH	SAYDON PHARMACEUTICAL INDUSTRIES (PVT) LTD.
WORCID	RAAZEE THERAPUTICS (PVT) LTD.
WORMAZOLE	SIZA INTERNATIONAL (PVT) LTD.
WORMDOX	MEDICEENA PHARMA (PVT) LTD.
WORMDOX	MEDICEENA PHARMA (PVT) LTD.
WORMIZOLE	EPLA LABORATORIES (PVT) LTD.
ZENZOL	JAWA PHARMACEUTICALS(PVT) LTD.
ZEWORM	WILSHIRE LABORATORIES (PVT) LTD.

Dose and treatment Course
The same dosage schedule applies to children and adults. The tablet may be chewed, swallowed, or crushed and mixed with food.

	Pinworm (enterobiasis)	Whipworm (trichuriasis)	Common Roundworm (ascariasis)	Hookworm
Dose	1 tablet, once	1 tablet morning and evening for 3 consecutive days.	1 tablet morning and evening for 3 consecutive days.	1 tablet morning and evening for 3 consecutive days.

If the patient is not cured three weeks after treatment, a second course of treatment is advised. No special procedures, such as fasting or purging, are required.